Barbara E . Stranger , Variation on Gene Expression Phenotypes
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منابع مشابه
Barbara E . Stranger , Variation on Gene Expression Phenotypes Relative
www.sciencemag.org (this information is current as of February 15, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/315/5813/848 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/315/5813/848/DC1 can be fou...
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Extensive studies are currently being performed to associate disease susceptibility with one form of genetic variation, namely, single-nucleotide polymorphisms (SNPs). In recent years, another type of common genetic variation has been characterized, namely, structural variation, including copy number variants (CNVs). To determine the overall contribution of CNVs to complex phenotypes, we have p...
متن کاملVariation on Gene Expression Phenotypes Relative Impact of Nucleotide and Copy
www.sciencemag.org (this information is current as of April 25, 2007 ): The following resources related to this article are available online at http://www.sciencemag.org/cgi/content/full/315/5813/848 version of this article at: including high-resolution figures, can be found in the online Updated information and services, http://www.sciencemag.org/cgi/content/full/315/5813/848/DC1 can be found ...
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UNLABELLED Genevar (GENe Expression VARiation) is a database and Java tool designed to integrate multiple datasets, and provides analysis and visualization of associations between sequence variation and gene expression. Genevar allows researchers to investigate expression quantitative trait loci (eQTL) associations within a gene locus of interest in real time. The database and application can b...
متن کاملSex-biased genetic effects on gene regulation in humans.
Human regulatory variation, reported as expression quantitative trait loci (eQTLs), contributes to differences between populations and tissues. The contribution of eQTLs to differences between sexes, however, has not been investigated to date. Here we explore regulatory variation in females and males and demonstrate that 12%-15% of autosomal eQTLs function in a sex-biased manner. We show that g...
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تاریخ انتشار 2013